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Case Study: SECAmb Live! Relaunch

To look at the theory that sildenafil, a phosphodiesterase sort 5 inhibitor that stops cGMP break down, could enhance nitric oxide supplement-mediated vasodilation and opposite endothelial disorder in long-term those that smoke. Flow-mediated dilation of the brachial artery and wrist postischemic reactive hyperemia (equally nitric oxide supplements-mediated replies) ended up measured pre and post sildenafil 50 mg and placebo in the dual-window blind, randomized, crossover examine in 9 men that had been chronic people who smoke (21 +Per- 3 load up decades). There was no substantial alteration of circulation-mediated dilation following possibly sildenafil (.18Per cent, 95Per centCI -1.7-2Percent) or placebo (.24Percent, 95%CI -2.8-3.3%) (S Equals .88 and .8, respectively). Sildenafil had no significant effect on sleeping lower arm the flow of blood or postischemic sensitive hyperemia (R Equates to .39 and .7, respectively). Relaxing heartrate and hypertension have been unaffected by sildenafil. Acute sildenafil administration did not enhance endothelial operate in persistent smoking cigarettes guys.

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Launch of the Dementia Training Centre

Sildenafil (Viagra) extends repolarisation in cardiovascular muscle, an impact that could lead to ventricular fibrillation (VF). Sildenafil (2 mg kilo(-1)) was presented by mouth to 12 mongrel dogs and, 24 l afterwards, these dogs were anaesthetised, thoracotomised and put through a 25 minute closure of the anterior climbing down coronary artery. Haemodynamic guidelines have been equivalent in this and also the manage group, but there have been a lesser number of and much less serious ventricular arrhythmias in the course of stoppage in the sildenafil party (VF 17 vs 60Per-cent ventricular rapid bests 140+Per-52 versus 437+/-127Percent and episodes of ventricular tachycardia 4.+Or-3.2 compared to 19.3+Per-7.7Per-cent, all P<0.05). However, reperfusion VF and indices of ischaemia severity (epicardial ST-segment mapping, inhomogeneity) were not modified by the drug. Sildenafil increased the QT interval, especially during ischaemia. Our conclusion is that ischaemia-induced ventricular arrhythmias are reduced by sildenafil, but this protection is less pronounced than that following cardiac pacing or exercise.

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onclick on show! learning technologies, london olympia

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dementia training centre: national awareness

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David Cameron: Dementia is “one of the greatest challenges of our time”, a “quiet crisis” and a “terrible disease” that “steals live and tears at the hearts of families”. In partnership with South London and Maudsley NHS Foundation Trust and King College London, Onclick has developed ‘The Dementia Training Centre’: a National training site for […]

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cervical screening conference: nw england

Onclick were excited to exhibit at the Buidling on Quality – Delivering Quality conference this week at the BT Convention Centre in Liverpool. Our Managing Director, Lester Cunningham, was also asked to give a talk about Onclick’s involvement in Cervical Screening e-learning. The conference, which was organised by the North West Cervical Screening QARC, was […]

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cwj launch: employment law updates

We are very happy to announce that Clarkson Wright and Jakes, a leading firm of Solicitors in Kent, has partnered with Onclick to launch a CWJ branded learnzone for their commercial clients and external users. Linked to their corporate website, the CWJ Learnzone provides a range of interactive e-learning courses including Equality & Diversity and […]

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macmillan: financial guidance

Onclick are proud to be working with Macmillan Cancer Support, developing a bespoke Macmillan-branded e-learning programme for their in-house Financial Guides. The programme provides up-to-date financial information for staff to use when advising and supporting those affected by cancer. Not only can it be used as a linear e-learning programme, but this course has been […]

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learning technologies: london olympia

So we’re giddy with excitement and super busy getting prepared for our first exhibition at Learning Technologies 2013, London Olympia! (January 29-30) Come and see us on Stand 53 – You can’t miss us. Just look out for pink! We’ll be covered in it! Now in it’s 14th year, Learning Technologies is Europe’s leading showcase […]

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cqc cleaning standards: e-learning programme

Onclick has been helping GP practices across Kent understand some of the Care Quality Commission (CQC) standards that they will need to comply with next year. Onclick was commissioned by the Kent & Medway GP staff training team to design and write a clear and easy-to-follow online and interactive learning programme. The e-training package launched […]

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